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Title   난소의 원발성 이행상피암종 - 1 증례 보고 - ( Transitional Cell Carcinoma of the Overy - A case report - )
Publicationinfo   1993 Jan; 025(03): 454-460.
Key_word   Transitional cell carainoma, Brenner tumor, Ovary, Chemotherapy
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Abstract   Transitional cell carcinoma(TCC) has been only recently recognized as one of the main types of ovarian carcinoma. The absence of benign Brenner component separates TCC from malignant Brenner tumor. TCCs are sufficiently distinctive to warrant their separation from both Brenner tumors and poorly differentiated ovarian carcinomas because the ovarian carcinomas containing predominant TCC pattern have an excellent response to chemotherapy and im- proved patient survivaL We report a case of ovarian TCC which occurred in a 49-year-old female. Grossly, the right ovary measured 7 x 5.5 x 3 cm and showed a poorly circumscribed reddish gray friable tumor. Histologically, the right ovarian tumor closely resemb1ed TCCs of the urinary tract with thick, blunt papillae with smooth luminal boarders and fibrovascular cores that extended into cystic spaces. The tumor cells were moderately differentiated and showed squamous differentiation, especially at the superficial portion of the tumor and infiltrative nests within the stroma. Immunohistochemically, the tumor cells were positive for cytokeratin and epithelial membrane antigen. Carcinoembryonic antigen was positive at the area of squamous differentiation. The patient showed multiple metastases within the pelvic and abdominal cavities at the time of operation, and their histopathalegic findings were similar to those of the right ovary. Although chemotherapy was perfonaed after operation, she expired 6 months later.
저 자   김준미(Joon Mee Kim),주영채(Young Chae Chu)